Gushchin G V, Shkhinek E K
Farmakol Toksikol. 1979 Nov-Dec;42(6):635-9.
Chronic administration of cholinomimetic (arecolin, pilocarpin, nicotin) and cholinolytic (bezohexonium, pedifen) drugs produces changes of different directions in the number of rosette-forming cells in the spleen of CBA mice immunized with sheep red blood cells. The analysis performed does not allow the effect of the drugs on immunologic processes to be accounted for by an immediate action on lymphoid cells or by an action of the function of the pituitary-adrenal system.
对用绵羊红细胞免疫的CBA小鼠,长期给予拟胆碱药(槟榔碱、毛果芸香碱、烟碱)和抗胆碱药(苄六甲铵、哌地芬)可使脾脏中玫瑰花结形成细胞数量发生不同方向的变化。所进行的分析表明,药物对免疫过程的影响不能用其对淋巴细胞的直接作用或垂体-肾上腺系统功能的作用来解释。