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肺部区域血容量对自主神经刺激的反应变化

Regional blood volume changes of the lungs in response to the vegetative nerves stimulation.

作者信息

Mazhbich B I, Kuzminykh L P, Pogodin A S

出版信息

Pflugers Arch. 1979 Nov;382(2):171-8. doi: 10.1007/BF00584219.

DOI:10.1007/BF00584219
PMID:574267
Abstract

Significant regional differences in the values of blood volume change response within one lobe of the lung upon the cervic sympathetic and parasympathetic nerves electrical stimulation have been demonstrated through the use of regional lung electroplethysmography method under the conditions of a minimal surgical trauma in dogs, cats, and rabbits kept in a supine position. The vascular component of the reaction has been isolated. It consists in blood volume increase in the lungs during the vagus stimulation and blood volume decrease during the sympathetic nerves stimulation. This response is very well manifested in central portions of the lung lobes and decreases progressively in peripheral direction. Blood volume changes due to different body positions relative to the gravitation direction have been demonstrated. Mechanisms of regional differences in blood volume changes have been discussed. The gravitation factor has been suggested to be also responsible for the formation of the neurogenic vasomotoric reaction in lungs.

摘要

通过在仰卧位的犬、猫和兔身上采用区域肺电阻抗容积描记法,在最小手术创伤的条件下,已证明在颈交感神经和副交感神经电刺激时,肺叶内血容量变化反应的值存在显著的区域差异。已分离出该反应的血管成分。其表现为迷走神经刺激时肺内血容量增加,交感神经刺激时血容量减少。这种反应在肺叶的中央部分表现得非常明显,并沿周边方向逐渐减弱。已证明了相对于重力方向的不同身体姿势导致的血容量变化。讨论了血容量变化区域差异的机制。有人提出重力因素也参与了肺神经源性血管运动反应的形成。

相似文献

1
Regional blood volume changes of the lungs in response to the vegetative nerves stimulation.肺部区域血容量对自主神经刺激的反应变化
Pflugers Arch. 1979 Nov;382(2):171-8. doi: 10.1007/BF00584219.
2
[Regional neurovasomotor reactions of pulmonary circulation].[肺循环的局部神经血管运动反应]
Biull Eksp Biol Med. 1979 Nov;88(11):520-2.
3
The effect of sympathetic nerve stimulation on pulmonary blood volume in isolated perfused lungs.
Acta Physiol Scand. 1971 Apr;81(4):448-54. doi: 10.1111/j.1748-1716.1971.tb04922.x.
4
[Blood filling and elasticity of pulmonary vessels after section and stimulation of the vagus nerve].[切断和刺激迷走神经后肺血管的血液充盈及弹性]
Biull Eksp Biol Med. 1983 Mar;95(3):5-8.
5
[Nervous control of the blood flow in the myocardial tissue].[心肌组织血流的神经控制]
Jpn Circ J. 1970 May;34(5):453-63. doi: 10.1253/jcj.34.453.
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[Control of coronary circulation by the autonomic nervous system].
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Autonomic nervous control of myoepithelial cells and secretion in submandibular gland of anaesthetized dogs.麻醉犬下颌下腺肌上皮细胞的自主神经控制与分泌
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Pulmonary vasodilator responses to vagal stimulation and acetylcholine in the cat.猫对迷走神经刺激和乙酰胆碱的肺血管舒张反应。
Circ Res. 1983 Jul;53(1):86-95. doi: 10.1161/01.res.53.1.86.
9
Haemodynamic responses to stimulation of the cardiac autonomic nerves in the anaesthetized cat with closed chest.在麻醉的开胸猫中,心脏自主神经受刺激时的血流动力学反应。
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Participation of the parasympathetic and sympathetic nerves in regulation of gallbladder motility in the dog.副交感神经和交感神经参与犬胆囊运动的调节。
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本文引用的文献

1
[ROLE OF THE PULMONARY VASOMOTOR NERVOUS SYSTEM].[肺血管运动神经系统的作用]
J Physiol (Paris). 1964 May-Jun;56:275.
2
The nervous control of the pulmonary circulation.肺循环的神经控制。
Naunyn Schmiedebergs Arch Exp Pathol Pharmakol. 1961;240:431-45. doi: 10.1007/BF00244936.
3
[Recent data on the pulmonary circulation].[关于肺循环的最新数据]
J Physiol (Paris). 1958 Apr-May;50(3):587-661.
4
The cite of action of nerves in the pulmonary vascular bed in the dog.狗肺血管床中神经的作用部位。
J Physiol. 1970 Aug;209(2):317-39. doi: 10.1113/jphysiol.1970.sp009167.
5
[Effect of vasomotor innervation on the pulmonary blood mass in dogs].[血管运动神经支配对犬肺血容量的影响]
J Physiol (Paris). 1969;61 Suppl 1:160-1.
6
[Vasomotor influences of the vagus nerve on the lungs].[迷走神经对肺部的血管运动影响]
Fiziol Zh SSSR Im I M Sechenova. 1971 Jun;57(6):879-87.
7
[Vasomotor efferent effects on the lungs (stimulation of the vagus nerve in the rabbit)].[血管舒缩传出神经对肺的作用(刺激家兔迷走神经)]
Biull Eksp Biol Med. 1971 Dec;72(12):3-6.
8
Influence of sympathetic stimulation and vasoactive substances on the canine pulmonary veins.交感神经刺激和血管活性物质对犬肺静脉的影响。
J Clin Invest. 1975 Aug;56(2):354-65. doi: 10.1172/JCI108100.