Preston N W
Lancet. 1976 May 15;1(7968):1065-7. doi: 10.1016/s0140-6736(76)92234-0.
It was estimated from a survey of 418 children aged three weeks to twelve years with bacteriologically confirmed whooping-cough that about 95% of vaccinated children are protected by current vaccine. Protection could be increased even further by the greater use of adsorbed rather than plain vaccine and by closer adherence to a vaccination schedule. The lower incidence of infection, resulting from widespread acceptance of this highly effective vaccine, would also greatly reduce the exposure of infants who are too young to be immunished themselves; and eradication ow whooping-cough would be in sight.
通过对418名年龄在3周龄至12岁之间经细菌学确诊为百日咳的儿童进行调查估计,约95%接种疫苗的儿童受到当前疫苗的保护。通过更多地使用吸附疫苗而非普通疫苗以及更严格地遵守疫苗接种计划,保护效果还可进一步提高。由于这种高效疫苗得到广泛接受,感染发病率降低,这也将大大减少太小而无法自行免疫的婴儿的接触风险;根除百日咳也将指日可待。