McFadyen I J, Forrest A P, Prescott R J, Golder M P, Groom G V, Fahmy D R, Griffiths K
Lancet. 1976 May 22;1(7969):1100-2. doi: 10.1016/s0140-6736(76)90064-7.
Multiple plasma-hormone concentrations were measured in sequential plasma-samples from six women with breast cancer and were compared to concentrations in six control women matched for age, years since menopause, and parity. All hormone concentrations in all the women studied were within normal limits. However, within the normal range the plasma-testosterone concentrations in each cancer patient were significantly higher than in each matched control.
对六名乳腺癌女性患者的连续血浆样本进行了多种血浆激素浓度的测量,并与六名年龄、绝经年限和产次相匹配的对照女性的浓度进行了比较。所有研究女性的所有激素浓度均在正常范围内。然而,在正常范围内,每位癌症患者的血浆睾酮浓度均显著高于每一位匹配的对照者。