Hansel S, Melekian B, Braive J P, Salet J
Ann Med Interne (Paris). 1979;130(10):481-5.
A 5-month-old infant presented with vomiting and severe hypoproteinemia from exsudation of proteins into the digestive tract, confirmed by isotopic tests. The association of hypertrophic edematous gastritis, interstitial jejunitis, and severe blood eosinophilia suggested the diagnosis of an exsudative eosinophil-type gastro-enteropathy. An allergy to cow's milk proteins was suspected because of the onset of the disorders at the time of weaning and the appearance of the eczema during the same period. Clinical, biological, and radiological recovery occurred after an exclusion diet and corticotherapy, and this persisted for 8 months, but the eczema remained. The authors describe a similar case (12) in an infant of 21 months with vomiting edema, and hypoproteinemia due to exsudation of proteins into the digestive tract. Radiological examination revealed the presence of hypertrophic gastritis. A relationship with Mentrier's disease had been suggested but not confirmed because of the rapid favourable outcome after a simple low protein diet.
一名5个月大的婴儿出现呕吐和因蛋白质渗入消化道导致的严重低蛋白血症,同位素检查证实了这一点。肥厚性水肿性胃炎、间质性空肠炎和严重的血液嗜酸性粒细胞增多症提示诊断为渗出性嗜酸性粒细胞型胃肠病。由于断奶时出现这些病症且同期出现湿疹,怀疑对牛奶蛋白过敏。排除饮食和皮质激素治疗后,临床、生物学和放射学症状恢复,且持续了8个月,但湿疹仍存在。作者描述了一名21个月大婴儿的类似病例(12),该婴儿因蛋白质渗入消化道出现呕吐、水肿和低蛋白血症。放射学检查显示存在肥厚性胃炎。有人提出与门脉性胃病有关,但由于单纯低蛋白饮食后迅速出现良好效果而未得到证实。