Prost A, Gorim de Ponsay E
Tropenmed Parasitol. 1979 Dec;30(4):477-81.
Between April 1977 and June 1978, 214 babies born of 210 mothers infected with Onchocerciasis, were examined at the maternity of Po Hospital (Upper Volta). In four of them (1.9%) dermal microfilariae of Onchocerca volvulus were found during the first week after birth. In two other cases microfilariae were seen in the tissue of the umbilical cord. All specimens from placentas and amniotic fluid gave negative results. The infected babies were reexamined monthly monthly from 2 to 18 months, depending on the cases. One child remained positive until the 6th month follow-up. The base-line examination of 5.757 children less than 2 years old from different villages in the WHO Onchocerciasis Control Programme in the Volta River Basin Area showed that 1% of children less than one year old and 2% of children of 12 to 23 months old were carriers of dermal microfilariae. These results indicate that in meso- or hyperendemic areas children less than one year old and carriers of microfilariae of Onchocerca volbulus may have been infected in utero. The existence of such cases, in an area of vector control, does not prove a residual vector borne transmission.
1977年4月至1978年6月期间,对上沃尔特波城医院产科的210名感染盘尾丝虫病的母亲所生的214名婴儿进行了检查。其中4名婴儿(1.9%)在出生后第一周发现了盘尾丝虫的皮肤微丝蚴。另外两例在脐带组织中发现了微丝蚴。所有胎盘和羊水标本检测结果均为阴性。根据具体情况,对感染婴儿从2个月至18个月每月进行复查。有一名儿童在随访至第6个月时仍呈阳性。对沃尔特河流域地区世界卫生组织盘尾丝虫病控制规划中不同村庄的5757名2岁以下儿童进行的基线检查显示,1%的1岁以下儿童和2%的12至23个月大的儿童为皮肤微丝蚴携带者。这些结果表明,在中度或高度流行地区,1岁以下儿童以及盘尾丝虫微丝蚴携带者可能在子宫内就已受到感染。在一个进行病媒控制的地区出现此类病例,并不能证明存在残余的病媒传播。