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Cerulenin resistance in a cerulenin-producing fungus. Isolation of cerulenin insensitive fatty acid synthetase.

作者信息

Kawaguchi A, Tomoda H, Okuda S, Awaya J, Omura S

出版信息

Arch Biochem Biophys. 1979 Oct 1;197(1):30-5. doi: 10.1016/0003-9861(79)90214-5.

DOI:10.1016/0003-9861(79)90214-5
PMID:575612
Abstract
摘要

相似文献

1
Cerulenin resistance in a cerulenin-producing fungus. Isolation of cerulenin insensitive fatty acid synthetase.
Arch Biochem Biophys. 1979 Oct 1;197(1):30-5. doi: 10.1016/0003-9861(79)90214-5.
2
[Mechanism of action of cerulenin on fatty acid synthetase and cerulenin resistance in a cerulenin-producing fungus].
Seikagaku. 1985 Mar;57(3):190-201.
3
Cerulenin resistance in a cerulenin-producing fungus. II. Characterization of fatty acid synthetase from Cephalosporium caerulens.产浅蓝菌素真菌对浅蓝菌素的抗性。II. 来自天蓝头孢霉的脂肪酸合成酶的特性
J Biochem. 1984 Jun;95(6):1705-12. doi: 10.1093/oxfordjournals.jbchem.a134784.
4
The antibiotic cerulenin, a novel tool for biochemistry as an inhibitor of fatty acid synthesis.抗生素浅蓝菌素,作为一种脂肪酸合成抑制剂,是生物化学领域的一种新型工具。
Bacteriol Rev. 1976 Sep;40(3):681-97. doi: 10.1128/br.40.3.681-697.1976.
5
Inhibition of 6-methylsalicyclic acid synthesis by the antibiotic cerulenin.抗生素浅蓝菌素对6-甲基水杨酸合成的抑制作用。
J Biochem. 1975 Dec;78(6):1149-52. doi: 10.1093/oxfordjournals.jbchem.a131010.
6
YAP1 confers resistance to the fatty acid synthase inhibitor cerulenin through the transporter Flr1p in Saccharomyces cerevisiae.在酿酒酵母中,YAP1 通过转运蛋白 Flr1p 赋予对脂肪酸合酶抑制剂浅蓝菌素的抗性。
Mol Gen Genet. 1999 Mar;261(2):346-53. doi: 10.1007/s004380050975.
7
The differential inhibition by cerulenin of fatty acid synthesis and elongation in the psychrophilic bacterium Micrococcus cryophilus.
Biochem Soc Trans. 1981 Feb;9(1):60-1. doi: 10.1042/bst0090060.
8
Inhibition of fatty acid synthesis by the antibiotic cerulenin. Specific inactivation of beta-ketoacyl-acyl carrier protein synthetase.抗生素浅蓝菌素对脂肪酸合成的抑制作用。β-酮酰-酰基载体蛋白合成酶的特异性失活。
Biochim Biophys Acta. 1973 Nov 29;326(2):155-6. doi: 10.1016/0005-2760(73)90241-5.
9
Mechanism of action of cerulenin on fatty acid synthetase. Effect of cerulenin on iodoacetamide-induced malonyl-CoA decarboxylase activity.浅蓝菌素对脂肪酸合成酶的作用机制。浅蓝菌素对碘乙酰胺诱导的丙二酰辅酶A脱羧酶活性的影响。
J Biochem. 1982 Jul;92(1):7-12. doi: 10.1093/oxfordjournals.jbchem.a133933.
10
Basis of cerulenin resistance of two strains of Candida albicans.
Microbiology (Reading). 1995 Jul;141 ( Pt 7):1553-8. doi: 10.1099/13500872-141-7-1553.

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Inactivation of the polyketide synthase, 6-methylsalicylic acid synthase, by the specific modification of Cys-204 of the beta-ketoacyl synthase by the fungal mycotoxin cerulenin.真菌霉菌毒素浅蓝菌素通过对β-酮酰基合成酶的半胱氨酸-204进行特异性修饰,使聚酮合酶(6-甲基水杨酸合成酶)失活。
Biochem J. 1998 Mar 1;330 ( Pt 2)(Pt 2):933-7. doi: 10.1042/bj3300933.
6
Purification and characterization of fatty acid synthetase from Cryptococcus neoformans.新型隐球菌脂肪酸合成酶的纯化与特性分析
Mycopathologia. 1996;136(2):75-84. doi: 10.1007/BF00437499.
7
Cerulenin-resistant mutants of Saccharomyces cerevisiae with an altered fatty acid synthase gene.脂肪酸合酶基因发生改变的酿酒酵母的浅蓝菌素抗性突变体。
Mol Gen Genet. 1994 Jul 8;244(1):90-6. doi: 10.1007/BF00280191.
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Philosophy of new drug discovery.新药研发理念
Microbiol Rev. 1986 Sep;50(3):259-79. doi: 10.1128/mr.50.3.259-279.1986.
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Cloning and characterization of a DNA gyrase B gene from Streptomyces sphaeroides that confers resistance to novobiocin.来自球形链霉菌的赋予新生霉素抗性的DNA促旋酶B基因的克隆与特性分析。
EMBO J. 1988 Jul;7(7):2255-9. doi: 10.1002/j.1460-2075.1988.tb03065.x.
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Membrane alteration is necessary but not sufficient for effective glutamate secretion in Corynebacterium glutamicum.膜改变对于谷氨酸棒杆菌中有效的谷氨酸分泌是必要的,但不是充分的。
J Bacteriol. 1990 Jun;172(6):3409-16. doi: 10.1128/jb.172.6.3409-3416.1990.