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[先天还是后天?精神病学中双生子研究的论断与方法]

[Inborn or acquired? The assertions and methods of twin research in psychiatry].

作者信息

Gmür M

出版信息

Schweiz Arch Neurol Neurochir Psychiatr. 1979;125(1):113-28.

PMID:575676
Abstract

Is Insanity inborn or acquired?--This question has become more actual in the last years as a consequence of progresses of psychotherapeutic and genetic research and the movement of antipsychiatry. This paper tries to clarify the dignity of the study of twins as contribution to an answer to this question. Some genetic terms are explicated as genotype, phenotype, monofactoriel and multifactoriel genetic transmission with sill. The significance of twin studies, of its contribution to the calculation of heritability and detection of environmental factors, and methodical problems as determination of zygosity and concordance, sampling method and correction of age are critically discussed.

摘要

精神错乱是先天的还是后天形成的?——由于心理治疗和遗传学研究的进展以及反精神病学运动,这个问题在过去几年变得更加现实。本文试图阐明双胞胎研究对于回答这个问题的价值。文中解释了一些遗传学术语,如基因型、表型、单因素和多因素遗传传递。对双胞胎研究的意义、其对遗传率计算和环境因素检测的贡献,以及诸如合子性和一致性的确定、抽样方法和年龄校正等方法学问题进行了批判性讨论。

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