Morgan A G, Polak A
Br Med J. 1969 Jan 4;1(5635):16-9. doi: 10.1136/bmj.1.5635.16.
Ten adults suffering from salicylate overdosage were treated successfully with a combination of sodium bicarbonate and acetazolamide to exploit the increase in salicylate clearance which is known to occur in very alkaline urine. The advantages of the method include the absence of important complications and the small volume of fluid required.
十名水杨酸盐过量的成年人通过碳酸氢钠和乙酰唑胺联合治疗成功治愈,这是为了利用在碱性很强的尿液中水杨酸盐清除率会增加这一原理。该方法的优点包括没有严重并发症且所需液体量少。