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乙酰唑胺和碳酸氢钠治疗成人水杨酸盐中毒

Acetazolamide and sodium bicarbonate in treatment of salicylate poisoning in adults.

作者信息

Morgan A G, Polak A

出版信息

Br Med J. 1969 Jan 4;1(5635):16-9. doi: 10.1136/bmj.1.5635.16.

Abstract

Ten adults suffering from salicylate overdosage were treated successfully with a combination of sodium bicarbonate and acetazolamide to exploit the increase in salicylate clearance which is known to occur in very alkaline urine. The advantages of the method include the absence of important complications and the small volume of fluid required.

摘要

十名水杨酸盐过量的成年人通过碳酸氢钠和乙酰唑胺联合治疗成功治愈,这是为了利用在碱性很强的尿液中水杨酸盐清除率会增加这一原理。该方法的优点包括没有严重并发症且所需液体量少。

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本文引用的文献

1
ALKALINE DIURESIS IN TREATMENT OF ASPIRIN POISONING.碱性利尿法治疗阿司匹林中毒
Br Med J. 1964 Oct 24;2(5416):1033-6. doi: 10.1136/bmj.2.5416.1033.
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TREATMENT OF SEVERE ASPIRIN POISONING WITHOUT DIALYSIS.
Lancet. 1964 Jun 27;2(7348):1409-12. doi: 10.1016/s0140-6736(64)91982-8.
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ACUTE SALICYLATE POISONING IN ADULTS.
Lancet. 1964 Jun 27;2(7348):1406-9. doi: 10.1016/s0140-6736(64)91981-6.
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THE TREATMENT OF SEVERE ASPIRIN POISONING.
Lancet. 1963 Aug 17;2(7303):329-31. doi: 10.1016/s0140-6736(63)92994-5.
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The excretion of salicylate.水杨酸盐的排泄。
Br J Pharmacol Chemother. 1955 Dec;10(4):484-9. doi: 10.1111/j.1476-5381.1955.tb00109.x.

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