源自犬肾的细胞系（MDCK）的分泌活性和致癌性。
Secretory activity and oncogenicity of a cell line (MDCK) derived from canine kidney.
作者信息
Leighton J, Brada Z, Estes L W, Justh G
出版信息
Science. 1969 Jan 31;163(3866):472-3. doi: 10.1126/science.163.3866.472.
PMID:5762397
Abstract
A cell line (MDCK) of dog kidney origin grows on a glass surface as a mosaic of epithelium with many multicellular hemispherical vesicles. The cells lining the blisters actively secrete into the cyst cavities. Suspensions of these cells injected intravenously in the chick embryo produce brain metastases resembling adenocarcinoma.
摘要
一种源自犬肾的细胞系（MDCK）在玻璃表面生长，形成由许多多细胞半球形囊泡构成的上皮镶嵌体。水泡内衬的细胞会主动分泌到囊腔中。将这些细胞的悬浮液静脉注射到鸡胚中会产生类似于腺癌的脑转移瘤。
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