埃佛勒斯峰医学研究：血浆中地高辛的测定及其在诊断地高辛中毒中的应用。
Everest MS: Measurement of digoxin in plasma and its use in diagnosis of digoxin intoxication.
作者信息
Grahame-Smith D G
出版信息
Br Med J. 1969 Feb 1;1(5639):286-9. doi: 10.1136/bmj.1.5639.286.
Abstract
A method for measuring the plasma-digoxin concentration uses the measurement of its inhibitory effect on (86)Rb uptake by human red cells in vitro. Patients receiving digoxin in whom there was no clinical evidence of digoxin intoxication had plasma digoxin concentrations ranging from 0.8 to 4.5 mmug./ml. Patients presenting with convincing clinical evidence of digoxin intoxication had plasma digoxin concentrations ranging from 4 to greater than 8 mmug./ml. It is suggested that the plasma digoxin concentration may be used as an aid in the diagnosis of digoxin intoxication.
摘要
一种测量血浆地高辛浓度的方法是利用体外测量其对人红细胞摄取(86)Rb的抑制作用。接受地高辛治疗但无地高辛中毒临床证据的患者，其血浆地高辛浓度范围为0.8至4.5微克/毫升。出现令人信服的地高辛中毒临床证据的患者，其血浆地高辛浓度范围为4至大于8微克/毫升。有人提出，血浆地高辛浓度可用于辅助诊断地高辛中毒。
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