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海葵毒素:与神经膜离子电导的相互作用。

Condylactis toxin: interaction with nerve membrane ionic conductances.

作者信息

Narahashi T, Moore J W, Shapiro B I

出版信息

Science. 1969 Feb 14;163(3868):680-1. doi: 10.1126/science.163.3868.680.

DOI:10.1126/science.163.3868.680
PMID:5762930
Abstract

A toxin from the Bermuda anemone Condylactis gigantea causes the early transient conductance change of crayfish giant axon membranes to persist without affecting the shape of its turning-on. The increase in late steadystate conductance is either not affected or slightly suppressed. The effect on the conductance components can adequately account for the prolonged action potential observed in the treated axon.

摘要

来自百慕大银莲花(Condylactis gigantea)的一种毒素会使小龙虾巨轴突膜早期短暂的电导变化持续存在,而不影响其开启的形态。后期稳态电导的增加要么不受影响,要么略有抑制。对电导成分的影响能够充分解释在经处理的轴突中观察到的动作电位延长现象。

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1
Condylactis toxin: interaction with nerve membrane ionic conductances.海葵毒素:与神经膜离子电导的相互作用。
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Lucifer Yellow slows voltage-gated Na+ current inactivation in a light-dependent manner in mice.
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J Physiol. 1982 Jan;322:529-39. doi: 10.1113/jphysiol.1982.sp014053.
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Effect of sea anemone toxins on the sodium inactivation process in crayfish axons.海葵毒素对小龙虾轴突钠失活过程的影响。
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