Hudson E A, Gauntlett J
Obstet Gynecol. 1977 Mar;49(3):280-6.
Analysis of 86 samples of amniotic fluid included a count of the total number of cells per cubic millimeter, the percent of fatty cells, and the lecithin/sphingomyelin ratio. In the period of gestation studied, 35 to 43 weeks, the average rise in the lecithin/sphingomyelin ratio with each week of gestation was only 0.22 (r = 0.27, P less than 0.02), but the correlations of the lecithin/sphingomyelin ratio with the number of fatty cells per cubic millimeter and with the nonfatty cells per cubic millimeter were highly significant (r = 0.64, P less than 0.001; and r = 0.53, P less than 0.001, respectively). The association of neutral fat-laden cells with the increase in lecithin could be due to a common origin from the skin of the fetus. Alternatively, exfoliation of fatty and nonfatty cells may be stimulated by the same mechanism that causes production of lung surfactant. It is suggested that surfactant lecithin becomes adsorbed onto the surface of the cells in amniotic fluid.
对86份羊水样本的分析包括每立方毫米细胞总数、脂肪细胞百分比以及卵磷脂/鞘磷脂比值的计数。在所研究的妊娠期（35至43周），卵磷脂/鞘磷脂比值每周的平均升高仅为0.22（r = 0.27，P < 0.02），但卵磷脂/鞘磷脂比值与每立方毫米脂肪细胞数量以及每立方毫米非脂肪细胞数量的相关性非常显著（分别为r = 0.64，P < 0.001；r = 0.53，P < 0.001）。富含中性脂肪的细胞与卵磷脂增加之间的关联可能是由于它们源自胎儿皮肤的共同起源。或者，脂肪细胞和非脂肪细胞的脱落可能受到与导致肺表面活性物质产生相同机制的刺激。有人提出，表面活性物质卵磷脂会吸附到羊水细胞表面。
