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豚鼠螺旋神经节的超微结构形态计量分析(作者译)

[Ultrastructural morphometric analysis of the spiral ganglion in guinea pigs (author's transl)].

作者信息

Merck W, Riede U N, Löhle E, Cürten I

出版信息

Arch Otorhinolaryngol. 1977 Feb 15;214(4):303-12. doi: 10.1007/BF00457471.

Abstract

This is the first morphometric analysis of the cochlear spiral ganglion. Therefore the ganglion was subdivided in precisely defined compartments. We found that the normal, untreated spiral ganglion in guinea pigs contains 58% ganglion cells of the granular type, 26% satellite cells and Schwann cells, 8.6% extracellular space, 6.4% myelinated nerve fibers and 1% ganglion cells of the filamentous type. The granular ganglion cell consists in 83% out of cytoplasm and in 17% out of nuclei. The cytoplasm is containing 13% ribosomes, 12% mitochondria, 10% RER, 2.1% Golgi apparatus, 1.3% lysosomes. Based on these quantitative datas we expect to detect alterations of the normal structure earlier and more precisely under pathophysiological conditions as before.

摘要

这是对耳蜗螺旋神经节的首次形态计量学分析。因此,将神经节精确划分为不同的区域。我们发现,正常未处理的豚鼠螺旋神经节包含58%的颗粒型神经节细胞、26%的卫星细胞和施万细胞、8.6%的细胞外空间、6.4%的有髓神经纤维以及1%的丝状型神经节细胞。颗粒型神经节细胞由83%的细胞质和17%的细胞核组成。细胞质中含有13%的核糖体、12%的线粒体、10%的粗面内质网、2.1%的高尔基体、1.3%的溶酶体。基于这些定量数据,我们期望在病理生理条件下比以往更早、更精确地检测到正常结构的改变。

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