Merck W, Riede U N, Löhle E, Cürten I
Arch Otorhinolaryngol. 1977 Oct 31;217(4):441-9. doi: 10.1007/BF00464466.
The cochlear spiral ganglion of rats consists of 61.8% granular ganglion cells, 22.4% satellite cells and Schwann cells, 9.3% extracellular space, 4.8% myelinated nerve fibers and 1.4% filamentous ganglion cells. The granular ganglion cells consist of 76% cytoplasmic components and 24% nuclei. Their cytoplasm contains 66.3% hyaloplasm, 11.4% mitochondria, 11% free ribosomes, 7.8% rough endoplasmic reticulum, 2.7% Golgi apparatus and 0.8% lysosomes. Comparing with morphometric data in guinea pigs, granular spiral ganglion cells in rats show some species dependent differences in their quantitative cytoarchitecture. They don't differ in their principal architectural pattern, especially in regard to the metabolism for energy and cell performance. The spiral ganglion cells of rats in contrast to those of guinea pigs do not show viral particles. Since it is impossible to evaluate with certainty the influence of viruses on the metabolism of infected cells, in our opinon rats are more suitable experimental animals for morphometric investigations of spiral ganglions.
大鼠的耳蜗螺旋神经节由61.8%的颗粒神经节细胞、22.4%的卫星细胞和施万细胞、9.3%的细胞外间隙、4.8%的有髓神经纤维以及1.4%的丝状神经节细胞组成。颗粒神经节细胞由76%的细胞质成分和24%的细胞核组成。其细胞质包含66.3%的透明质、11.4%的线粒体、11%的游离核糖体、7.8%的粗面内质网、2.7%的高尔基体以及0.8%的溶酶体。与豚鼠的形态测量数据相比，大鼠的颗粒螺旋神经节细胞在定量细胞结构上表现出一些物种依赖性差异。它们在主要结构模式上没有差异，尤其是在能量代谢和细胞功能方面。与豚鼠不同，大鼠的螺旋神经节细胞未显示病毒颗粒。由于无法确定病毒对受感染细胞代谢的影响，我们认为大鼠是更适合用于螺旋神经节形态测量研究的实验动物。
