Oertel Y C, Johnson F B
Arch Pathol Lab Med. 1977 Jun;101(6):321-6.
In 1950 the term "sclerosing lipogranuloma" was introduced to designate a praticular subcutaneous granulomatous reaction that was believed to be a "local reactive process following injury to adipose tissue." Subsequent reports have shown that exogenous lipid injections probably are responsible for this lesion. We have studied 23 cases involving penis, scrotum, spermatic cord, and perineum, nine of which had been previously reported. We have been able to identify paraffin hydrocarbons by means of infrared-absorption spectrophotometry in 21 of these cases. We belive this entity should be redefined as a "local reactive process following injection of exogenous lipids into the subcutaneous tissues." In conventional microscopical sections, the lesion must be differentiated from adenomatoid tumor, sclerosing liposarcoma, and lymphangioma.
1950年引入了“硬化性脂肪肉芽肿”这一术语，用于指一种特殊的皮下肉芽肿反应，当时认为这是“脂肪组织损伤后的局部反应过程”。随后的报告表明，外源性脂质注射可能是导致这种病变的原因。我们研究了23例累及阴茎、阴囊、精索和会阴的病例，其中9例此前已有报告。通过红外吸收分光光度法，我们在其中21例病例中鉴定出了石蜡烃。我们认为，这个实体应重新定义为“将外源性脂质注射到皮下组织后的局部反应过程”。在传统的显微镜切片中，该病变必须与腺瘤样瘤、硬化性脂肪肉瘤和淋巴管瘤相鉴别。
