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新生儿、其母亲血清及脐血中的生长调节素A和B。

Somatomedin A and B in serum from neonates, their mothers and cord blood.

作者信息

Svan H, Hall K, Ritzén M, Takano K, Skottner A

出版信息

Acta Endocrinol (Copenh). 1977 Jul;85(3):636-43. doi: 10.1530/acta.0.0850636.

Abstract

Somatomedin A by radioreceptor assay and somatomedin B by radioimmunoassay were measured in serum from women immediately after parturition and from their newborns. The mean levels of somatomedin A in both mothers (0.54 U/ml) and infants (0.50 U/ml) were significantly decreased compared to a reference group consisting of 21 non-pregnant women (0.91 U/ml). There was no difference between the mothers and their children. The mean somatomedin B value in serum from the mothers (63.9 microgram/ml) was above that found in non-pregnant women (19.2 microgram/ml) and the mean value in cord blood and serum from the infants (7.1 microgram/ml) was below it. A positive correlation was noted between somatomedin A and B in cord blood; r = 0.78. The combined somatomedin A and B values in cord blood were positively correlated to birth weight (r = 0.51, P less than 0.05).

摘要

采用放射受体分析法测定产后即刻母亲血清中的生长调节素A,并采用放射免疫分析法测定新生儿血清中的生长调节素B。与由21名未怀孕女性组成的对照组(0.91 U/ml)相比,母亲(0.54 U/ml)和婴儿(0.50 U/ml)血清中生长调节素A的平均水平均显著降低。母亲和孩子之间没有差异。母亲血清中生长调节素B的平均水平(63.9微克/毫升)高于未怀孕女性(19.2微克/毫升),而婴儿脐带血和血清中的平均水平(7.1微克/毫升)低于此值。脐带血中生长调节素A和B之间存在正相关;r = 0.78。脐带血中生长调节素A和B的联合值与出生体重呈正相关(r = 0.51,P<0.05)。

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