脉孢菌中类似物抗性与氨基酸营养缺陷型之间的相互作用。
Interaction between analogue resistance and amino acid auxotrophy in Neurospora.
作者信息
Kinsey J A, Stadler D R
出版信息
J Bacteriol. 1969 Mar;97(3):1114-7. doi: 10.1128/jb.97.3.1114-1117.1969.
Abstract
A new p-fluorophenylalanine resistant mutant of Neurospora (fpr-1) was isolated. It is unaffected by the suppressor of a previously described resistance mutant, mtr. The fpr-1 locus is on linkage group V, tightly linked to act-2. The expression of resistance to p-fluorophenylalanine by fpr-1 can be suppressed by genes controlling a requirement for lysine or arginine. The suppression seems to involve an increased sensitivity of the lysine and arginine auxotrophs to p-fluorophenylalanine.
摘要
分离出了一种新的对氟苯丙氨酸具有抗性的脉孢菌突变体（fpr - 1）。它不受先前描述的抗性突变体mtr的抑制子影响。fpr - 1基因座位于连锁群V上，与act - 2紧密连锁。控制赖氨酸或精氨酸需求的基因可以抑制fpr - 1对氟苯丙氨酸的抗性表达。这种抑制似乎涉及赖氨酸和精氨酸营养缺陷型对氟苯丙氨酸的敏感性增加。
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2
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