白血病豚鼠血浆中的DNA聚合酶活性。
DNA polymerase activity in plasma from leukaemic guinea-pigs.
作者信息
Hallinan F M, Maclean N
出版信息
Br J Cancer. 1976 Apr;33(4):419-26. doi: 10.1038/bjc.1976.67.
Abstract
Measurement of DNA polymerase in leukaemic guinea-pig plasms reveals the presence of low levels of sedimentable and non-sedimentable enzymic activities. Since the sedimentable DNA polymerase is ribonuclease sensitive, uses poly(C).oligo(dG) as template, and bands in a sucrose density gradient at 1-17 g/ml it is thought to be the GPLV-associated reverse transcriptase. The soluble DNA polymerase is stimulated by ribonuclease and is probably of cellular origin.
摘要
对白血病豚鼠血浆中DNA聚合酶的测量显示存在低水平的可沉降和不可沉降的酶活性。由于可沉降的DNA聚合酶对核糖核酸酶敏感，以聚（C）·寡聚（dG）作为模板，并且在蔗糖密度梯度中位于1-17 g/ml处形成条带，因此被认为是与GPLV相关的逆转录酶。可溶性DNA聚合酶受到核糖核酸酶的刺激，可能起源于细胞。
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本文引用的文献
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Attempts to adapt leukemia L2C from inbred to noninbred guinea pigs.将白血病L2C从近交豚鼠适应至非近交豚鼠的尝试。
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DNA polymerases in human lymphoblastoid cells infected with simian sarcoma virus.感染猿猴肉瘤病毒的人淋巴母细胞中的DNA聚合酶
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Induction of type C viruses in cultured guinea pig cells.在培养的豚鼠细胞中诱导C型病毒。
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