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Ⅲ型高脂蛋白血症

Type 3 hyperlipoproteinaemia.

作者信息

Borrie P

出版信息

Br Med J. 1969 Jun 14;2(5658):665-7. doi: 10.1136/bmj.2.5658.665.

DOI:10.1136/bmj.2.5658.665
PMID:5783124
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1983670/
Abstract

Eighteen patients with type III hyperlipoproteinaemia, diagnosed on the basis of skin lesions, serum lipids, and lipoprotein electrophoresis, have been fully investigated over a period of 15 years. The incidence of coronary artery disease was only slightly increased, and was not increased at all among first-degree relatives. Peripheral occlusive arterial disease was probably more common. An increased incidence of carbohydrate intolerance was found in neither the patients nor their relatives. The effects of treatment on the skin were uniformly good.

摘要

根据皮肤损害、血脂及脂蛋白电泳诊断出的18例III型高脂蛋白血症患者，已在15年期间接受了全面检查。冠状动脉疾病的发病率仅略有增加，一级亲属中根本没有增加。外周闭塞性动脉疾病可能更为常见。在患者及其亲属中均未发现糖耐量异常的发病率增加。治疗对皮肤的效果始终良好。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f450/1983670/b754a970a727/brmedj02036-0042-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f450/1983670/9800be3d22f9/brmedj02036-0042-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f450/1983670/b754a970a727/brmedj02036-0042-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f450/1983670/9800be3d22f9/brmedj02036-0042-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f450/1983670/b754a970a727/brmedj02036-0042-b.jpg

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1
Type 3 hyperlipoproteinaemia.Ⅲ型高脂蛋白血症
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2
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2
Clinical features of type III hyperlipoproteinemia: analysis of 64 patients.III型高脂蛋白血症的临床特征：64例患者分析
Clin Investig. 1993 May;71(5):362-6. doi: 10.1007/BF00186624.
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Cholesterolester accumulation.胆固醇酯蓄积

本文引用的文献

1
STUDIES OF MALE SURVIVORS OF MYOCARDIAL INFARCTION DUE TO "ESSENTIAL" ATHEROSCLEROSIS. 3. CORNEAL ARCUS: INCIDENCE AND RELATION TO SERUM LIPIDS AND LIPOPROTEINS.“原发性”动脉粥样硬化所致心肌梗死男性幸存者的研究。3. 角膜弓：发病率及其与血清脂质和脂蛋白的关系。
Can Med Assoc J. 1964 Oct 17;91(16):835-9.
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ELEVATION OF SERUM-CHOLESTEROL BY AN ANABOLIC STEROID.一种合成代谢类固醇导致血清胆固醇升高。
Lancet. 1964 Apr 11;1(7337):828-9. doi: 10.1016/s0140-6736(64)93015-6.
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The relationship of serum uric acid to risk factors in coronary heart disease.
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Mutants, hyperlipoproteinaemia, and coronary artery disease.突变体、高脂蛋白血症与冠状动脉疾病。
Br Med J. 1971 Apr 24;2(5755):187-92. doi: 10.1136/bmj.2.5755.187.
5
Xanthomatosis, hyperlipoproteinaemia (type II, Fredrickson), gout, cardiac infarction.黄瘤病、高脂蛋白血症（II型，弗雷德里克森分类法）、痛风、心肌梗死。
Proc R Soc Med. 1971 Jan;64(1):59-60. doi: 10.1177/003591577106400136.
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[Hyperlipoproteinemia and coronary disease. Occurrence, distribution of types, age and sex factors].[高脂蛋白血症与冠心病。发病率、类型分布、年龄及性别因素]
Klin Wochenschr. 1972 Feb 1;50(3):139-48. doi: 10.1007/BF01486938.
7
Study of the pedigree of a patient with type 3 hyperlipoproteinaemia and sinking prebeta lipoprotein.3型高脂蛋白血症伴前β脂蛋白降低患者的家系研究。
J Clin Pathol. 1973 Mar;26(3):163-6. doi: 10.1136/jcp.26.3.163.
Am J Med. 1968 Oct;45(4):520-8. doi: 10.1016/0002-9343(68)90168-x.
4
Hyperlipidaemic xanthomatosis. I. Increased risk of death from ischaemic heart disease in first degree relatives of 53 patients with essential hyperlipidaemia and xanthomatosis.高脂血症性黄瘤病。I. 53例原发性高脂血症和黄瘤病患者一级亲属缺血性心脏病死亡风险增加。
J Med Genet. 1968 Mar;5(1):4-8. doi: 10.1136/jmg.5.1.4.
5
Primary hyperlipoproteinemia: the clinico-chemical classification of the most common types.原发性高脂蛋白血症：最常见类型的临床化学分类
Clin Chim Acta. 1968 Feb;19(2):181-90. doi: 10.1016/0009-8981(68)90325-2.
6
Fat transport in lipoproteins--an integrated approach to mechanisms and disorders.脂蛋白中的脂肪运输——机制与疾病的综合研究方法
N Engl J Med. 1967 Jan 26;276(4):215-25 contd. doi: 10.1056/NEJM196701262760406.
7
Polyacrylamide gels of increasing concentration gradient for the electrophoresis of lipoproteins.用于脂蛋白电泳的浓度梯度递增的聚丙烯酰胺凝胶。
Clin Chim Acta. 1969 Jan;23(1):189-201. doi: 10.1016/0009-8981(69)90026-6.