Escande J P
Rev Rhum Mal Osteoartic. 1977 Jul-Sep;44(7-9):455-9.
The Gougerot-Sjögren syndrome is giving rise to an everincreasing number of publications. Since the initial work by Gougerot in France and Sjögren in Sweden, the most important publications have been coming from the United States of America, particularly the series from the NIH at Bethesda. Since Bunim, Talal, Bloch and colleagues have taken up this topic, the conception of the disease which has become established is that of an auto-immune condition which or may not be associated with a rheumatoid polyarthritis or related diseases. It may be asked whether such a conception does in fact permit a better approach to patients suffering from the Gougerot-Sjögren syndrome. It might seem more useful to separate the exocrine syndromes from the concomittant immunitary symptoms more clearly. A further important problem is that raised by the perfection of the means of detecting the Gougerot-Sjögren syndrome. This poses a key problem : that of the borderlines of this syndrome.
古热罗-舍格伦综合征引发的出版物数量日益增多。自法国的古热罗和瑞典的舍格伦开展最初的研究工作以来，最重要的出版物一直来自美国，尤其是贝塞斯达国立卫生研究院的系列研究。自从布尼姆、塔拉勒、布洛赫及其同事着手研究这一课题以来，已确立的疾病概念是一种自身免疫性疾病，它可能与类风湿性多关节炎或相关疾病有关，也可能无关。人们可能会问，这样的概念是否真的能让我们更好地治疗患有古热罗-舍格伦综合征的患者。更明确地将外分泌综合征与伴随的免疫症状区分开来似乎更有用。另一个重要问题是由检测古热罗-舍格伦综合征方法的完善所引发的。这带来了一个关键问题：该综合征的边界问题。
