Saleh M A, Zaki O A, Moustafa R, Abdel-Hafiz A, Abbadi M, El-Damarawy N A
Arzneimittelforschung. 1977;27(8):1584-6.
The effects of volume replacement with 4% gelatin containing 1% glycine at pH 5.8 and 6.4 on the changes in mean arterial blood pressure (MABP) and blood levels of glucose, lactate and urea following acute haemorrhage in dogs were studied. Comparison was made with dogs given homologous blood. Dogs bled 30% of blood volume, maintained in shock for 30 min, and infused with gelatin solutions, showed values of MABP, blood glucose, lactate and urea nitrogen insignificantly different from dogs similarly bled and infused with homologous blood. The responses obtained in dogs infused with gelatin at pH 5.8 were better than at pH 6.4.
研究了用含1%甘氨酸、pH值为5.8和6.4的4%明胶进行容量替代对犬急性出血后平均动脉血压（MABP）以及血糖、乳酸和尿素血水平变化的影响。并与输注同源血液的犬进行了比较。犬失血30%血容量，休克维持30分钟后输注明胶溶液，其MABP、血糖、乳酸和尿素氮值与同样失血并输注同源血液的犬相比无显著差异。pH值为5.8时输注明胶的犬所获得的反应比pH值为6.4时更好。
