Krause V W
Fortschr Med. 1977 Aug 25;95(32):1984-6.
As in patients with high pituitary prolactin secretion disturbances of the spermatogenesis are observed, we picked out from our patients with low sperm count those showing hyperprolactinemia without pituitary adenoma. They were treated for 50 days with 2-brom-alpha-ergocryptin (Pravidel, Sandoz AG, Nürnberg), which selectively inhibits prolactin release. Following treatment, in 7 cases an increase in sperm count was observed, while in 2 cases a decrease occurred. 4 cases with azoospermia showed no alteration. No explanation for the possible stimulation of spermatogenesis can be given today.
正如在垂体泌乳素分泌过高的患者中观察到精子发生紊乱一样，我们从精子数量低的患者中挑选出那些无垂体腺瘤但表现为高泌乳素血症的患者。用选择性抑制泌乳素释放的2-溴-α-麦角隐亭（帕罗维德，山德士股份公司，纽伦堡）对他们进行了50天的治疗。治疗后，7例患者的精子数量增加，而2例患者的精子数量减少。4例无精子症患者无变化。目前无法对精子发生可能受到的刺激作出解释。
