Bhattacharjee J
Histochem J. 1976 Jan;8(1):63-70. doi: 10.1007/BF01004006.
In the optic cup of early mouse embryos, carbonic anhydrase activity is seen only in the pigment epithelial cells. During the late prenatal period the enzyme appears in the Müller cells, first in the perikarya. During the postnatal development the enzyme activity appears in the radial processes of the Müller cells starting at the vitreal border along with the separation of the outer retinal layers. This is followed by increased activity in the plexiform layers, presumably in the lateral processes. Carbonic anhydrase localization in pigment epithelial and Müller cells attains the adult pattern at about 16 days corresponding with the initiation of retinal function.
在早期小鼠胚胎的视杯中，碳酸酐酶活性仅见于色素上皮细胞。产前后期，该酶出现在米勒细胞中，首先出现在胞体。产后发育过程中，随着视网膜外层的分离，酶活性从玻璃体边界开始出现在米勒细胞的放射状突起中。随后，在神经纤维层（可能在侧面突起中）活性增加。色素上皮细胞和米勒细胞中的碳酸酐酶定位在约16天时达到成年模式，这与视网膜功能的开始相对应。
