Kikugawa K, Minoshima K
Vox Sang. 1978;34(5):281-90. doi: 10.1111/j.1423-0410.1978.tb02483.x.
Filter columns (Imugard filters) packed with cotton wool prepared from Gossypium barbadense cotton removed 95--100% of leukocytes from packed red cell suspensions. Recovery of red cells was about 95%. The efficacy was similar for ACD and heparinized blood. Blood was filtered below 10 degrees C within 30 min under pressures of less than 0.2 kg/cm2. The shape and functions of the red cells were not altered by filtration. No pyrogenic or toxic substances, and little particulate matter were eluted from the filters.
装有由海岛棉制备的脱脂棉的过滤柱（Imugard过滤器）可从浓缩红细胞悬液中去除95%至100%的白细胞。红细胞的回收率约为95%。对于ACD血和肝素化血，其效果相似。血液在低于10摄氏度的温度下，于30分钟内、压力小于0.2千克/平方厘米的条件下进行过滤。过滤未改变红细胞的形态和功能。过滤器未洗脱出发热原或有毒物质，且洗脱的颗粒物很少。
