1,5-二咖啡酰奎宁酸（绿原酸）对急性乙醇处理大鼠血清和肝脏中胆固醇水平的影响。
Effect of 1,5-dicaffeylquinic acid (cynarine) on cholesterol levels in serum and liver of acute ethanol-treated rats.
作者信息
Wójcicki J
出版信息
Drug Alcohol Depend. 1978 Mar;3(2):143-5. doi: 10.1016/0376-8716(78)90028-5.
PMID:580239
Abstract
The effect of 1,5-dicaffeylquinic acid (Cynarine) on total cholesterol levels in serum and liver of acute ethanol-treated rats was studied. Male Wister rats were administered ethyl alcohol, 6 g/kg per day by gavage over three days. In rats treated with ethanol alone, the serum and hepatic cholesterol showed a significant rise of 44 and 75%, respectively. In rats receiving ethanol and Cynarine simultaneously, a distinct reduction of the serum and hepatic cholesterol levels was observed.
摘要
研究了1,5-二咖啡酰奎宁酸（绿原酸）对急性乙醇处理大鼠血清和肝脏中总胆固醇水平的影响。雄性Wistar大鼠通过灌胃给予乙醇，每天6克/千克，持续三天。仅用乙醇处理的大鼠，其血清和肝脏胆固醇分别显著升高了44%和75%。在同时接受乙醇和绿原酸的大鼠中，观察到血清和肝脏胆固醇水平明显降低。
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