Bost R G, Stolt R A
J Toxicol Environ Health. 1976 May;1(5):823-7. doi: 10.1080/15287397609529381.
Distinctive chromatin bodies appearing in interphase nuclei of mammalian female cells have been found in most mammalian species. The positive correlation between sex chromatin masses and mammalian female tissue presents an almost ideal criterion for sex determination of mammalian tissues. Previous studies indicate that this positive correlation exists in fresh and formalin-fixed, paraffin-embedded normal and tumor tissue of humans, as well as in fresh squash preparations of normal and tumor tissues of rodents. In this experiment we have shown that it is also possible to determine sex in formalin-fixed, paraffin-embedded normal and tumor tissue of the rat.
在大多数哺乳动物物种中，已发现哺乳动物雌性细胞的间期核中出现独特的染色质体。性染色质质量与哺乳动物雌性组织之间的正相关关系为哺乳动物组织的性别鉴定提供了几乎理想的标准。先前的研究表明，这种正相关关系存在于人类新鲜的以及经福尔马林固定、石蜡包埋的正常和肿瘤组织中，也存在于啮齿动物正常和肿瘤组织的新鲜压片标本中。在本实验中，我们已表明，在经福尔马林固定、石蜡包埋的大鼠正常和肿瘤组织中确定性别也是可行的。
