生长抑制与各种青霉素和头孢菌素与金黄色葡萄球菌结合之间的相关性。
Correlation between growth inhibition and the binding of various penicillins and cephalosporins to Staphylococcus aureus.
作者信息
Edwards J R, Park J T
出版信息
J Bacteriol. 1969 Aug;99(2):459-62. doi: 10.1128/jb.99.2.459-462.1969.
Abstract
The concentration of penicillin (or cephalosporin) required to achieve a given rate of binding to Staphylococcus aureus H correlates well with that required for inhibition of growth. This result suggests that the irreversible binding of penicillins and cephalosporins to cells is responsible for their biological activity.
摘要
实现与金黄色葡萄球菌H特定结合率所需的青霉素（或头孢菌素）浓度与抑制生长所需的浓度密切相关。这一结果表明，青霉素和头孢菌素与细胞的不可逆结合是其生物活性的原因。
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Correlation between growth inhibition and the binding of various penicillins and cephalosporins to Staphylococcus aureus.生长抑制与各种青霉素和头孢菌素与金黄色葡萄球菌结合之间的相关性。
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The nature of the binding of penicillin by bacterial cells.细菌细胞对青霉素的结合性质。
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The binding of penicillin in relation to its cytotoxic action. II. The reactivity with penicillin of resistant variants of streptococci, pneumococci, and staphylococci.青霉素结合与其细胞毒性作用的关系。II. 链球菌、肺炎球菌和葡萄球菌耐药变体与青霉素的反应性。
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A note on the use of radioactive penicillin.
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The association of the penicillin-binding component of Staphylococcus aureus with a lipid fraction.
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