Clarke D B
Thorax. 1969 May;24(3):342-7. doi: 10.1136/thx.24.3.342.
An experimental technique is described whereby the isolated lung is perfused by means of its respiratory excursion. No perfusion pump is required. Lungs were subjected to positive and negative pressure inflation in a sealed box and were perfused with either blood or blood and low molecular weight dextran at 36° C. and 23°C. In all experiments gross histological changes and pulmonary oedema developed within four hours. Marginally longer perfusions were obtained than in a control series in which a roller pump was used.
本文描述了一种实验技术，通过该技术可利用离体肺的呼吸运动进行灌注，无需灌注泵。将肺置于密封箱中进行正压和负压充气，并在36℃和23℃下用血液或血液与低分子量右旋糖酐进行灌注。在所有实验中，四小时内均出现明显的组织学变化和肺水肿。与使用滚轴泵的对照系列相比，灌注时间略有延长。
