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三氯乙烯作业工人的染色体研究(作者译)

[Chromosome studies on trichloroethylene workers (author's transl)].

作者信息

Konietzko H, Haberlandt W, Heilbronner H, Reill G, Weichardt H

出版信息

Arch Toxicol. 1978 Jun 16;40(3):201-6. doi: 10.1007/BF00364651.

Abstract

On the basis of lymphocyte cultures, chromosome studies were carried out on 28 degreasers under different trichloroethylene load. Nine of these cases showed pathological rates of hypodiploid cells, but otherwise normal caryotypes; one case had a caryotype 47,XY,+mar (small metacentric extrachromosome). In these nine cases the trichloroethylene load, but not the exposure periods on the working place were significantly higher than in the control group.

摘要

基于淋巴细胞培养,对28名处于不同三氯乙烯负荷下的脱脂工人进行了染色体研究。其中9例显示亚二倍体细胞的病理率,但核型其他方面正常;1例核型为47,XY,+mar(小的中着丝粒额外染色体)。在这9例中,三氯乙烯负荷显著高于对照组,但在工作场所的暴露时间并非如此。

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