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低剂量放射性碘治疗甲状腺毒症

Treatment of thyrotoxicosis with low doses of radioactive iodine.

作者信息

Goolden A W, Fraser T R

出版信息

Br Med J. 1969 Aug 23;3(5668):442-3. doi: 10.1136/bmj.3.5668.442.

DOI:10.1136/bmj.3.5668.442
PMID:5811653
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1984197/
Abstract

In a series of 156 thyrotoxic patients treated with low doses of radioactive iodine the therapeutic dose was calculated by means of a sliding scale in which the dose level was varied according to the estimated size of the gland. Of the patients so treated 56.5% achieved a remission with a single dose of (131)I. The incidence of hypothyroidism at one year was 5%.

摘要

在一组接受低剂量放射性碘治疗的156例甲状腺毒症患者中,治疗剂量通过一个滑动量表来计算,其中剂量水平根据估计的腺体大小而变化。在接受如此治疗的患者中,56.5%通过单次剂量的碘-131实现了病情缓解。一年时甲状腺功能减退的发生率为5%。

相似文献

1
Treatment of thyrotoxicosis with low doses of radioactive iodine.低剂量放射性碘治疗甲状腺毒症
Br Med J. 1969 Aug 23;3(5668):442-3. doi: 10.1136/bmj.3.5668.442.
2
Radioactive iodine (125I) therapy for thyrotoxicosis.放射性碘(¹²⁵I)治疗甲状腺毒症。
N Engl J Med. 1971 Nov 11;285(20):1099-104. doi: 10.1056/NEJM197111112852001.
3
Effect of pretreatment with carbimazole in patients with thyrotoxicosis subsequently treated with radioactive iodine.卡比马唑预处理对随后接受放射性碘治疗的甲状腺毒症患者的影响。
Br Med J. 1969 Aug 23;3(5668):443-4. doi: 10.1136/bmj.3.5668.443.
4
[Late side effects of radioactive iodine therapy in hyperthyroidism].[放射性碘治疗甲状腺功能亢进症的晚期副作用]
Rinsho Hoshasen. 1973 Aug;48(8):527-41.
5
Long-term results from graded low dose radioactive iodine therapy for thyrotoxicosis.分级低剂量放射性碘治疗甲状腺毒症的长期结果。
Clin Endocrinol (Oxf). 1986 Feb;24(2):217-22. doi: 10.1111/j.1365-2265.1986.tb00765.x.
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Comparison of high and low dosage levels of 131-I in the treatment of thyrotoxicosis.131碘高剂量与低剂量治疗甲状腺毒症的比较。
N Engl J Med. 1967 Sep 14;277(11):559-62. doi: 10.1056/NEJM196709142771102.
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Comparison of large and small doses of radioactive 131-I in the treatment of patients with cardiac damage associated with thyrotoxicosis.
Nucl Med (Stuttg). 1971 Apr 30;10(1):55-68.
8
Relation between the 6- and 24-hour thyroidal 131-I uptake and the control of thyrotoxicosis by radioactive 131-I therapy.6小时和24小时甲状腺131碘摄取量与放射性131碘治疗甲状腺毒症控制情况之间的关系。
S Afr Med J. 1973 Aug 4;47(30):1356-8.
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Effect of pretreatment with carbimazole on early outcome following radio-iodine (131I) therapy.卡比马唑预处理对放射性碘(¹³¹I)治疗后早期结局的影响。
Eur J Nucl Med. 1984;9(10):464-6. doi: 10.1007/BF00563170.
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Propranolol and radioactive iodine in the treatment of thyrotoxicosis.普萘洛尔与放射性碘治疗甲状腺毒症
Br J Pharmacol. 1970 May;39(1):198P.

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The early development of transient and permanent hypothyroidism following radioiodine therapy for hyperthyroid Graves' disease.放射性碘治疗甲状腺功能亢进症(Graves病)后短暂性和永久性甲状腺功能减退的早期发展
Can Med Assoc J. 1984 May 1;130(9):1141-4.
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Br Med J. 1970 Mar 21;1(5698):745-8. doi: 10.1136/bmj.1.5698.745.
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Low-dose radioiodine given six-monthly in Graves' disease.格雷夫斯病患者每六个月给予低剂量放射性碘治疗。
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Low-dose 131I in treatment of Graves' disease.低剂量¹³¹I治疗Graves病
J R Soc Med. 1985 Mar;78(3):197-202. doi: 10.1177/014107688507800305.

本文引用的文献

1
RADIOIODINE THERAPY IN THYROTOXICOSIS; A REVIEW OF 908 CASES.甲状腺毒症的放射性碘治疗;908例病例综述。
Scott Med J. 1964 Dec;9:505-13. doi: 10.1177/003693306400901201.
2
RISING INCIDENCE OF HYPOTHYROIDISM AFTER RADIOACTIVE-IODINE THERAPY IN THYROTOXICOSIS.甲状腺毒症放射性碘治疗后甲状腺功能减退症发病率上升
N Engl J Med. 1964 Nov 12;271:1037-42. doi: 10.1056/NEJM196411122712004.
3
THYROTOXICOSIS TREATED BY SURGERY OR IODINE-131. WITH SPECIAL REFERENCE TO DEVELOPMENT OF HYPOTHYROIDISM.手术或碘 - 131治疗甲状腺毒症。特别提及甲状腺功能减退症的发生。
Br Med J. 1964 Apr 18;1(5389):1005-10. doi: 10.1136/bmj.1.5389.1005.
4
Incidence of hypothyroidism and recurrences following I-131 treatment of hyperthyroidism.I-131治疗甲亢后甲状腺功能减退症的发生率及复发情况。
Acta Radiol (Stockh). 1961 Oct;56:275-88. doi: 10.3109/00016926109172822.
5
Treatment of hyperthyroidism with sodium iodide I-131.用碘-131化钠治疗甲状腺功能亢进症。
JAMA. 1966 Aug 22;197(8):605-10.
6
Clinical and radiobiological consequences of therapeutic thyroid irradiation.治疗性甲状腺照射的临床和放射生物学后果。
Proc R Soc Med. 1966 Jul;59(7):599-602. doi: 10.1177/003591576605900706.