Loutit J F, Ash P J
Br J Cancer. 1978 Jul;38(1):24-33. doi: 10.1038/bjc.1978.160.
Generalized lymphosarcomatosis (leukaemia) of non-thymic type occurs in mice bearing 90Sr or 239Pu or 226Ra. Tumours passaged from such mice have been tested for tumour-associated transplantation antigens that could provoke a protective immunity which would be expected if such antigens were determined by virus activated by the irradiation. Sub-threshold doses of living syngeneic tumour, large doses of living allogeneic tumour and large doses of killed syngeneic tumour were without protective effect. This suggests that viruses observed electron micrographically in such tumours are passengers and not causative.
非胸腺型全身性淋巴肉瘤病（白血病）发生于携带90锶、239钚或226镭的小鼠。已对从此类小鼠传代的肿瘤进行检测，以寻找肿瘤相关移植抗原，这些抗原可能引发保护性免疫，若此类抗原由辐射激活的病毒所决定，便可预期会产生这种免疫。亚阈值剂量的活同基因肿瘤、大剂量的活异基因肿瘤以及大剂量的灭活同基因肿瘤均无保护作用。这表明，在此类肿瘤中通过电子显微镜观察到的病毒是过客而非致病因素。
