Chalon J, Tang C K, Ramanathan S, Klein G, O'Meara J B, Turndorf H
Arch Pathol Lab Med. 1978 Dec;102(12):631-4.
Histiocytes counted in smears made from the tracheobronchial washings of 208 patients with malignant melanomas were found to be 3.12 times more numerous than in a control group comparable in sex, age (decades), and smoking habit but without any type of prediagnosed malignant lesion. The discovery of this phenomenon may lead to the development of a new method for the evaluation of therapeutic methods in patients with melanotic lesions. It may open novel pathways for the investigation of cell-mediated immunity in patients with certain forms of malignant disease.
在对208例恶性黑色素瘤患者的气管支气管灌洗涂片进行组织细胞计数时发现，其组织细胞数量是一个在性别、年龄（以十年计）和吸烟习惯方面与之匹配但无任何预先诊断出的恶性病变的对照组的3.12倍。这一现象的发现可能会促成一种评估黑素病变患者治疗方法的新方法的开发。它可能为研究某些形式恶性疾病患者的细胞介导免疫开辟新途径。
