加蓬咝蝰（Bitis gabonica）毒液对血液凝固、血小板及纤维蛋白溶解酶系统的影响。
Effect of gaboon viper (Bitis gabonica) venom on blood coagulation, platelets, and the fibrinolytic enzyme system.
作者信息
Forbes C D, Turpie A G, Ferguson J C, McNicol G P, Douglas A S
出版信息
J Clin Pathol. 1969 May;22(3):312-6. doi: 10.1136/jcp.22.3.312.
Abstract
The action of the venom of the gaboon viper (Bitis gabonica) on blood coagulation, platelets, and the fibrinolytic enzyme system was studied. The results confirm that the venom of Bitis gabonica has a marked anticoagulant action in vitro. The venom appears to impair clot formation by a direct proteolytic action on fibrinogen, releasing soluble breakdown products.
摘要
研究了加蓬咝蝰（Bitis gabonica）毒液对血液凝固、血小板及纤维蛋白溶解酶系统的作用。结果证实，加蓬咝蝰毒液在体外具有显著的抗凝作用。该毒液似乎通过对纤维蛋白原的直接蛋白水解作用来损害凝块形成，释放可溶性降解产物。
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