Atallah M M, Geddes I C
Middle East J Anaesthesiol. 1978 Oct;5(2):85-91.
Metabolism of halothane following its repeated administration, was studied in three patients by estimating the blood bromide concentrations before, during and after halothane anaesthesia. In one patient, the blood halothane concentration was measured during and after its administration. The fraction of halothane metabolised was found to be increased after its repeated administration. This was proved by the rapid clearance of halothane and the increased blood bromide concentration.
通过评估三位患者在氟烷麻醉前、麻醉期间和麻醉后的血溴浓度，研究了氟烷重复给药后的代谢情况。在一位患者身上，还测量了给药期间和给药后的血氟烷浓度。结果发现，氟烷重复给药后，其代谢分数增加。这通过氟烷的快速清除和血溴浓度的升高得到了证实。
