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1
Incorporation of [14C] histidine into homocarnosine and carnosine of frog brain in vivo and in vitro.[14C]组氨酸在体内和体外掺入青蛙脑的高肌肽和肌肽的情况。
Biochem J. 1969 Sep;114(3):585-8. doi: 10.1042/bj1140585.
2
[Intensity of label incorporation from [1,4-14C]putrescine into homocarnosine in the brain of rats of various ages].
Ukr Biokhim Zh (1978). 1986 Sep-Oct;58(5):75-7.
3
UPTAKE OF CARNOSINE AND HOMOCARNOSINE BY RAT BRAIN SLICES.大鼠脑切片对肌肽和高肌肽的摄取
Arch Biochem Biophys. 1964 Jan;104:160-5. doi: 10.1016/s0003-9861(64)80049-7.
4
Analysis of carnosine, homocarnosine, and other histidyl derivatives in rat brain.
J Neurochem. 1990 Aug;55(2):446-52. doi: 10.1111/j.1471-4159.1990.tb04156.x.
5
A sensitive specific enzymatic-fluorometric assay for homocarnosine.一种用于高肌肽的灵敏特异的酶促荧光测定法。
J Neurochem. 1973 Aug;21(2):387-96. doi: 10.1111/j.1471-4159.1973.tb04258.x.
6
The effect of various agents in the levels of homocarnosine in rat brain.各种药物对大鼠脑内高肌肽水平的影响。
Biochem Pharmacol. 1968 Apr;17(4):640-2. doi: 10.1016/0006-2952(68)90281-5.
7
Histidine-containing dipeptide deficiency links to hyperactivity and depression-like behaviors in old female mice.组氨酸二肽缺乏与老年雌性小鼠的多动和抑郁样行为有关。
Biochem Biophys Res Commun. 2024 Oct 15;729:150361. doi: 10.1016/j.bbrc.2024.150361. Epub 2024 Jul 5.
8
[Metabolism of homocarnosine and gamma-amino butyric acid in different regions of rat brain under hyperoxia].
Ukr Biokhim Zh (1978). 1978 Sep-Oct;50(5):573-5.
9
[Homocarnosine content and homocarnosine-carnosine synthetase activity in brain areas of hyperoxic rats].
Ukr Biokhim Zh (1978). 1979 Sep-Oct;51(5):483-6.
10
[Content of homocarnosine, gamma-amino butyric acid and histidine in brain tissue of different age normal rabbits and under hyperoxia].[不同年龄正常家兔及高氧状态下家兔脑组织中同型肌肽、γ-氨基丁酸和组氨酸的含量]
Ukr Biokhim Zh (1978). 1979 Mar-Apr;51(2):135-8.

引用本文的文献

1
Carnosinase activity of human gastrointestinal mucosa.人胃肠道黏膜的肌肽酶活性。
Gut. 1975 Aug;16(8):585-9. doi: 10.1136/gut.16.8.585.

本文引用的文献

1
Body size and tissue respiration.身体大小与组织呼吸
Biochim Biophys Acta. 1950 Jan;4(1-3):249-69. doi: 10.1016/0006-3002(50)90032-1.
2
Enzymatic synthesis of carnosine and related beta-alanyl and gamma-aminobutyryl peptides.肌肽及相关β-丙氨酰和γ-氨基丁酰肽的酶促合成。
J Biol Chem. 1959 Dec;234:3210-8.
3
OCCURRENCE OF HOMOCARNOSINE (GAMMA-AMINOBUTYRYLHISTIDINE) IN THE BRAIN OF RANA ESCULENTA.食用蛙脑中高肌肽(γ-氨基丁酰组氨酸)的存在情况。
J Neurochem. 1964 Aug;11:619. doi: 10.1111/j.1471-4159.1964.tb11460.x.
4
UPTAKE OF CARNOSINE AND HOMOCARNOSINE BY RAT BRAIN SLICES.大鼠脑切片对肌肽和高肌肽的摄取
Arch Biochem Biophys. 1964 Jan;104:160-5. doi: 10.1016/s0003-9861(64)80049-7.
5
The distribution of homocarnosine in mammals.
Arch Biochem Biophys. 1962 Nov;99:210-3. doi: 10.1016/0003-9861(62)90002-4.
6
Isolation of gamma-aminobutyrylhistidine (homocarnosine) from brain.从大脑中分离γ-氨基丁酰组氨酸(同型肌肽)。
J Biol Chem. 1961 Feb;236:499-502.
7
Synthesis of homocarnosine in muscle in vivo.体内肌肉中肌肽的合成。
Biochim Biophys Acta. 1961 Jul 8;50:570-2. doi: 10.1016/0006-3002(61)90018-x.
8
Carnosine-anserine synthetase of muscle. II. Specificity and inhibition studies with amino acid analogs.肌肉中的肌肽 - 鹅肌肽合成酶。II. 氨基酸类似物的特异性及抑制研究。
Bull Soc Chim Biol (Paris). 1958;40(12):1727-35.
9
Carnosineanserine synthetase of muscle. I. Preparation and properties of soluble enzyme from chick muscle.肌肉中的肌肽-鹅肌肽合成酶。I. 鸡肌肉中可溶性酶的制备及性质
Biochim Biophys Acta. 1959 Jan;31(1):47-55. doi: 10.1016/0006-3002(59)90437-8.
10
[Beta-alanine and its compound in biological media].[生物介质中的β-丙氨酸及其化合物]
Ann Soc R Sci Med Nat Brux. 1953;6(3-4):157-254.

[14C]组氨酸在体内和体外掺入青蛙脑的高肌肽和肌肽的情况。

Incorporation of [14C] histidine into homocarnosine and carnosine of frog brain in vivo and in vitro.

作者信息

Yockey W C, Marshall F D

出版信息

Biochem J. 1969 Sep;114(3):585-8. doi: 10.1042/bj1140585.

DOI:10.1042/bj1140585
PMID:5820644
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1184931/
Abstract
  1. Homocarnosine, carnosine and histidine were determined in brain from several species and the results compared with values in the literature. 2. [(14)C]Homocarnosine and [(14)C]carnosine were isolated from frog brain after intracerebral injection of [(14)C]histidine in vivo. 3. Whole frog brain, incubated in vitro with l-[(14)C]histidine, formed labelled homocarnosine and carnosine. 4. A frog brain homogenate or supernatant fraction catalysed the incorporation of l-[(14)C]histidine into homocarnosine and carnosine. 5. The results indicate that brain tissue can synthesize homocarnosine and carnosine.
摘要
  1. 测定了几种物种大脑中的同型肌肽、肌肽和组氨酸,并将结果与文献中的数值进行了比较。2. 在体内向蛙脑内注射[(14)C]组氨酸后,从蛙脑中分离出[(14)C]同型肌肽和[(14)C]肌肽。3. 用l-[(14)C]组氨酸在体外孵育完整的蛙脑,生成了标记的同型肌肽和肌肽。4. 蛙脑匀浆或上清液部分催化了l-[(14)C]组氨酸掺入同型肌肽和肌肽。5. 结果表明脑组织能够合成同型肌肽和肌肽。