[32P-incorporation in adenosine phosphates of the rat brain after oral application of vincamine for 2 weeks (author's transl)].

The 32P-incorporation into the adenosine phosphates AMP, ADP and ATP of the rat brain after an oral administration of a daily dose of 20 mg/kg 14,15-dihydro14 beta-hydroxy-(3 alpha,16 alpha)-eburnamenine-14-carbonic acid methylester (vincamine; Vincapront) during two weeks was determined. The concentrations of the three adenosine phosphates did not change. After the administration of vincamine the increase in the 32P-incorporation into AMP and ADP was statistically significant. The results obtained are discussed in regard to an acceleration of the pentose phosphate shunt and an activation of adenylate kinase.