Vachal E, Wegst A, Preston D, Tomita T
J Surg Oncol. 1979;11(4):283-8. doi: 10.1002/jso.2930110402.
A therapeutic dose of 131I was given to a 53-year-old man with thyrotoxicosis three and one-half hours prior to death. The distribution of 131I in the thyroid gland was studied by autoradiography, and the radioactivity in various fresh tissues was measured. Radioactivity was distributed evenly throughout the colloid; small amounts were present in follicular cells. Radioactivity was not localized to the periphery of colloid follicles as observed in an earlier report. Papillary projections were associated with increased radioactivity. Decreased radioactivity was associated with oxyphilic cells. Measurement of 131I in individual tissues showed that per gram of tissue the thyroid gland contained approximately 50 times that of intestine and spleen and approximately 100 times that of liver and bone.
在一名53岁甲状腺毒症男性患者死亡前三小时半给予了治疗剂量的131I。通过放射自显影研究了131I在甲状腺中的分布，并测量了各种新鲜组织中的放射性。放射性均匀分布于整个胶体中；滤泡细胞中有少量存在。放射性并未像早期报告中所观察到的那样定位于胶体滤泡的周边。乳头状突起与放射性增加有关。嗜酸性细胞与放射性降低有关。对各个组织中131I的测量表明，每克组织中甲状腺所含的131I约为肠道和脾脏的50倍，约为肝脏和骨骼的100倍。
