Prakash P, St Clair L E, Romack F E
Acta Histochem. 1976;57(2):282-90. doi: 10.1016/S0065-1281(76)80055-4.
An attempt was made to visualize the sites of accumulation and distribution of 131I and 125I in the organs and tissues of swine by a modified autoradiographic dipping technique. Radioactivity was substantially higher with the injection of 125I than that of 131I. There was a tendency in all tissues for concentration of radioiodine to vary with the age of the animals. Concentration was evident in the lung, muscle, liver, pancreas, intestinal mucosa, thymus and spleen, in addition to the known accumulation sites, such as the adrenal, pituitary and gonads. The isotopes were concentrated at the striated border of the epithelial cells of the duodenum. The submandibular gland had a marked concentration in the collecting ducts and a lesser one in the secretory parenchyma of the gland. The most radioactive organ examined was the thyroid gland. The readioactivity was consistently higher in the follicular epithelial cells than in the connective tissue between the follicles. The bound radioiodine formed rings over the colloid-cell interface.
采用改良的放射自显影浸渍技术，试图可视化猪的器官和组织中¹³¹I和¹²⁵I的蓄积和分布部位。注射¹²⁵I后的放射性明显高于¹³¹I。所有组织中放射性碘的浓度都有随动物年龄变化的趋势。除了肾上腺、垂体和性腺等已知的蓄积部位外，肺、肌肉、肝脏、胰腺、肠黏膜、胸腺和脾脏中也有明显的放射性碘蓄积。同位素集中在十二指肠上皮细胞的纹状缘。下颌下腺在集合管中有明显的放射性碘蓄积，而在腺的分泌实质中蓄积较少。检查的放射性最强的器官是甲状腺。滤泡上皮细胞中的放射性始终高于滤泡之间的结缔组织。结合的放射性碘在胶体 - 细胞界面形成环状。
