Maslenikov V, Acevedo de Mendilaharsu S, Azambuja N
Acta Neurol Latinoam. 1977;23(1-4):103-15.
Among 20 patients with symptoms of cerebrovascular insufficiency, dissociation between memory disturbances and cognitive functions, and PEG studies, there were 13 cases showing atrophy of the hippocampus. The neurological and psychological studies included memory functions tests, IQ, and the analysis of language and praxia. Complementary tests included standard EEG records, EEGs obtained with nasopharingeal electrodes and PEG tomography with selective filling of both temporal horns, in order to demonstrate the inner and lower surface of the temporal lobes. The volume of the Ammon horn was reduced in 13 cases. Hippocampal atrophy was unilateral in 11 patients and bilateral in 2. The fact that hippocampal atrophy was demonstrated by PEG studies in 13 out of 20 cases, appears to be highly significant. This clinico-neuroradiological correlation seems to indicate that hippocampal atrophy, following ischemia in the deep distal vertebro-basilar-posterior cerebral territory, disturbs the function of axial structures (Papez circuit or limbic system) apparently leading to the disturbances of memory functions observed in this group of patients.
在20例有脑血管供血不足症状、记忆障碍与认知功能分离以及进行了PEG研究的患者中，有13例显示海马萎缩。神经学和心理学研究包括记忆功能测试、智商以及语言和运用能力分析。补充检查包括标准脑电图记录、鼻咽电极脑电图以及双侧颞角选择性充盈的PEG断层扫描，以显示颞叶的内表面和下表面。13例患者的海马角体积减小。11例患者海马萎缩为单侧，2例为双侧。在20例中有13例通过PEG研究证实有海马萎缩，这一事实似乎具有高度显著性。这种临床神经放射学相关性似乎表明，在椎基底动脉-大脑后动脉深部分支缺血后，海马萎缩会干扰轴突结构（帕佩兹环路或边缘系统）的功能，显然导致了该组患者出现记忆功能障碍。
