Marshall W C, Peckham C S, Dudgeon J A, Sheppard S, Smithells R W, Weatherall J A
Lancet. 1976 Jun 5;1(7971):1231-3. doi: 10.1016/s0140-6736(76)92173-5.
Data from the National Congenital Rubella Surveillance Programme showed that 44% of children with congenital rubella reported to the programme were born to primiparae. This high proportion is thought to be due to the fact that there was a two-fold increase in the rate of abortion for rubella in pregnancy for women with two or more children. This higher incidence of congenital rubella in firstborns emphasises the need for rubella vaccination prior to a woman's first pregnancy.
国家先天性风疹监测项目的数据显示,该项目所报告的先天性风疹患儿中,44%为初产妇所生。这一高比例被认为是由于两个或更多孩子的女性孕期风疹流产率增加了两倍。头胎婴儿先天性风疹的较高发病率凸显了女性首次怀孕前进行风疹疫苗接种的必要性。