Kreutzberger A, Leyke-Röhling S
Arzneimittelforschung. 1978;28(11):2051-4.
By condensation of 1,1-diethylguanidine (1) with beta-diketones (2), the 2-(diethylamino)pyrimidines (3) are formed. Aside from beta-diketones substituted by aliphatic (2 a--e), mixed aliphatic-aromatic (2f), and pure aromatic-carbocyclic (2g and h) moieties, also those carrying aromatic-heterocyclic (2i and 4) substitutents are amenable to this reaction.
通过1,1 - 二乙基胍（1）与β - 二酮（2）缩合，生成2 - （二乙氨基）嘧啶（3）。除了被脂肪族（2a - e）、脂肪族 - 芳香族混合（2f）以及纯芳香族 - 碳环（2g和h）部分取代的β - 二酮外，那些带有芳香族 - 杂环（2i和4）取代基的β - 二酮也适用于此反应。
