Shuster S
Lancet. 1976 Jun 19;1(7973):1328-9. doi: 10.1016/s0140-6736(76)92657-x.
It is argued that the close endocrine control of human sebaceous glands and the likely effects of acne on selection indicate that both gland and disease have persisted because they are biologically useful. Two possibilities are proposed: sebum may provide precursor substrates for metabolism and synthesis by the epidermis of compounds of both local and systemic importance; and the adjuvent properties of corynebacteria which colonise the active sebaceous glands of acne may facilitate certain general immunological membrane.
有人认为,人类皮脂腺的紧密内分泌控制以及痤疮对选择的可能影响表明,腺体和疾病之所以持续存在,是因为它们在生物学上是有用的。提出了两种可能性:皮脂可能为表皮代谢和合成具有局部和全身重要性的化合物提供前体底物;在痤疮活跃皮脂腺中定殖的棒状杆菌的辅助特性可能促进某些一般免疫膜。