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正常人和动物血清中抗短小棒状杆菌抗体。

Antibody to Corynebacterium parvum in normal human and animal sera.

作者信息

Wolberg G, Duncan G S, Adlam C, Whisnant J K

出版信息

Infect Immun. 1977 Mar;15(3):1004-7. doi: 10.1128/iai.15.3.1004-1007.1977.

DOI:10.1128/iai.15.3.1004-1007.1977
PMID:870426
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC421475/
Abstract

Using a microtiter bacterial agglutination test, we have estimated antibodies to Corynebacterium parvum in "normal" human and "normal" and immune animal sera. Widely differing levels of C. parvum antibodies were found in the normal human sera. The median titer for all 310 human sera was 1:128, whereas that for the 1- to 17-year and 18- to 50-year subgroups was 1:64 and 1:512, respectively. Antibody titers in the various animal species were generally much lower.

摘要

通过微量滴定细菌凝集试验，我们已对“正常”人血清以及“正常”和免疫动物血清中的微小棒状杆菌抗体进行了评估。在正常人类血清中发现了水平差异很大的微小棒状杆菌抗体。310份人类血清的中位数效价为1:128，而1至17岁和18至50岁亚组的中位数效价分别为1:64和1:512。各种动物物种中的抗体效价通常要低得多。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d6f6/421475/2eb9dc1bbdeb/iai00207-0327-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d6f6/421475/2eb9dc1bbdeb/iai00207-0327-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d6f6/421475/2eb9dc1bbdeb/iai00207-0327-a.jpg

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本文引用的文献

1
Diphtheroid infections of man.人类的类白喉杆菌感染
Ann Intern Med. 1969 May;70(5):919-29. doi: 10.7326/0003-4819-70-5-919.
2
Corynebacterium parvum: a synonym for Propionibacterium acnes?短小棒状杆菌：痤疮丙酸杆菌的同义词？
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Corynebacterium parvum as an immunotherapeutic anticancer agent.短小棒状杆菌作为一种免疫治疗性抗癌药物。
寻常性炎性痤疮中多种趋化因子对多形核白细胞的趋化效率
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Interferon production and lymphocyte stimulation in human leucocyte cultures stimulated by Corynebacterium parvum.短小棒状杆菌刺激人白细胞培养物中的干扰素产生及淋巴细胞刺激作用
Clin Exp Immunol. 1978 Jun;32(3):471-6.
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Biotyping of Propionibacterium acnes isolated from normal human facial skin.从正常人面部皮肤分离出的痤疮丙酸杆菌的生物分型
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Immune response modulation by colonization of germfree rats with Propionibacterium acnes.痤疮丙酸杆菌定殖于无菌大鼠对免疫反应的调节作用。
Infect Immun. 1979 Nov;26(2):473-8. doi: 10.1128/iai.26.2.473-478.1979.
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Experimental intraocular malignancy: the effect of intracameral perfusion.实验性眼内恶性肿瘤：前房灌注的影响
Trans Am Ophthalmol Soc. 1979;77:63-79.
Semin Oncol. 1974 Dec;1(4):367-78.
4
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Gan. 1973 Feb;64(1):7-14.
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Mchanisms of antitumor action of Corynebacterium parvum: nonspecific tumor cell destruction at site of immunologically mediated sensitivity reaction to C. parvum.短小棒状杆菌的抗肿瘤作用机制：在对短小棒状杆菌免疫介导的敏感性反应部位对肿瘤细胞进行非特异性破坏。
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