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[干燥综合征中不寻常的自身免疫和肿瘤相关疾病]

[Unusual autoimmune and neoplastic associated diseases in Sjogren's syndrome].

作者信息

Reiner M, Goldhirsch A, Kaplan E, Luscieti P, Pedrinis E, Noseda G

出版信息

Schweiz Med Wochenschr. 1979 Nov 24;109(45):1741-2.

PMID:583182
Abstract

In an unselected series of 12 patients with Sjögren's syndrome the following autoimmune diseases were observed: severe myxedema due to Hashimotos thyroiditis in four, subclinical thyroid hypofunction in one, diffuse hyperthyroidism in one, glomerulonephritis in two, chronic active hepatitis in one, lupus erythematodes disseminatus in three (one with idiopathic thrombocytopenic purpura), classical rheumatoid arthritis in two. A rare familial occurrence was seen in two sisters. The only male in this group exhibited coexistence of a benign adenolymphoma of the parotid gland (Warthin's tumor) with a malignant non-Hodgkin lymphoma.

摘要

在一组未经挑选的12例干燥综合征患者中,观察到以下自身免疫性疾病:4例因桥本甲状腺炎导致的严重黏液性水肿,1例亚临床甲状腺功能减退,1例弥漫性甲状腺功能亢进,2例肾小球肾炎,1例慢性活动性肝炎,3例播散性红斑狼疮(其中1例伴有特发性血小板减少性紫癜),2例典型类风湿关节炎。在两姐妹中发现了罕见的家族性发病情况。该组中唯一的男性表现为腮腺良性腺淋巴瘤(沃辛瘤)与恶性非霍奇金淋巴瘤并存。

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