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[作为动物反应类型(高级神经活动水平)函数的Wistar大鼠的血细胞计数、白细胞碱性磷酸酶活性和血糖水平]

[Blood count, leukocyte alkaline phosphatase activity, and blood sugar levels in Wistar rats as a function of the reaction type (level of higher nervous activity) of the animal].

作者信息

Freund D, Freund J L, Hofmann R, Glanzmann P, Kahlau F

出版信息

Arzneimittelforschung. 1979;29(10):1513-6.

PMID:583213
Abstract

The corpuscular blood composition, ALP activity and glucose level of 20 E+ and 20 E- adult male Wistar rats were measured without stress. We wanted to find differences due to the specific reaction type--emotive/non-emotive--of the animals. E+ animals had higher counts of small erythrocytes and a higher total number of leucocytes than E- rats. When the compositions of the blood of several inbred strains were compared, the composition of the red blood, total number of leucocytes and lymphocytes of E- -Wistar rats and E- -Sprague-Dawley rats were most similar. Differences in the activity of the ALP and in the glucose levels we found are similar to those in literature on this topic. When measured in a condition of inactivity the lower glucose values of E+ Wistar rats correspond to the excretion of smaller amounts of urinary catecholamines. Our findings, as well as those mentioned in the literature, confirm the assumption that the reaction type--which corresponds to the type of higher nervous activity--influences all functions of the organism including the composition of the blood.

摘要

在无应激状态下,对20只E+成年雄性Wistar大鼠和20只E-成年雄性Wistar大鼠的血细胞成分、碱性磷酸酶(ALP)活性及血糖水平进行了测量。我们想找出由于动物特定反应类型——情绪化/非情绪化——所导致的差异。E+大鼠的小红细胞计数和白细胞总数高于E-大鼠。当比较几种近交系大鼠的血液成分时,E- -Wistar大鼠和E- -Sprague-Dawley大鼠的红细胞成分、白细胞总数及淋巴细胞最为相似。我们发现的碱性磷酸酶活性和血糖水平差异与该主题的文献报道相似。在静止状态下测量时,E+ Wistar大鼠较低的血糖值与较少的尿儿茶酚胺排泄量相对应。我们的研究结果以及文献中提到的结果证实了这样一种假设,即与高级神经活动类型相对应的反应类型会影响机体的所有功能,包括血液成分。

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