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1
Cellular injury and carcinogenesis. Alkylation of ribonucleic acid of rat liver by diethylnitrosamine and n-butylmethylnitrosamine in vivo.细胞损伤与致癌作用。二乙基亚硝胺和正丁基甲基亚硝胺在体内对大鼠肝脏核糖核酸的烷基化作用。
Biochem J. 1964 Apr;91(1):35-42. doi: 10.1042/bj0910035.
2
Methylation of nuclear proteins by dimethylnitrosamine and by methionine in the rat in vivo.大鼠体内二甲基亚硝胺和蛋氨酸对核蛋白的甲基化作用。
Biochem J. 1971 Oct;124(4):725-39. doi: 10.1042/bj1240725.
3
Metabolism of diethylnitrosamine by human liver slices in vitro.
Nature. 1970 Oct 10;228(5267):173-4. doi: 10.1038/228173a0.
4
Alkylation of rat liver RNA by cyclic N-nitrosamines in vivo.体内环状N-亚硝胺对大鼠肝脏RNA的烷基化作用。
J Natl Cancer Inst. 1966 Oct;37(4):401-7.
5
[The biochemical mechanism of action of carcinogenic N-nitroso compounds].
Arztl Forsch. 1972 Jun 10;26(6):197-202.
6
Formation by diethylnitrosamine and persistence of O4-ethylthymidine in rat liver DNA in vivo.二乙基亚硝胺在大鼠肝脏DNA中诱导形成O4-乙基胸苷及其在体内的持久性
Cancer Lett. 1980 Jul;10(1):1-6. doi: 10.1016/0304-3835(80)90058-0.
7
Reactive intermediates from nitrosamines.亚硝胺产生的反应中间体。
Adv Exp Med Biol. 1981;136 Pt B:1027-35.
8
Nitrosamine-induced carcinogenesis. The alkylation of N-7 of guanine of nucleic acids of the rat by diethylnitrosamine, N-ethyl-N-nitrosourea and ethyl methanesulphonate.亚硝胺诱导的致癌作用。二乙基亚硝胺、N-乙基-N-亚硝基脲和甲磺酸乙酯对大鼠核酸鸟嘌呤N-7位的烷基化作用。
Biochem J. 1971 Dec;125(3):841-7. doi: 10.1042/bj1250841.
9
Alkylation of nuclear proteins in rat liver by diethylnitrosamine.二乙基亚硝胺对大鼠肝脏核蛋白的烷基化作用。
Cell Mol Biol. 1982;28(3):353-61.
10
Alkylation of nucleic acids of rat liver and lung by deuterated N-nitrosodiethylamine in vivo.
J Natl Cancer Inst. 1971 Oct;47(4):789-95.

引用本文的文献

1
What Makes a Potent Nitrosamine? Statistical Validation of Expert-Derived Structure-Activity Relationships.什么造就了强效亚硝胺？专家推导的结构-活性关系的统计验证。
Chem Res Toxicol. 2022 Nov 21;35(11):1997-2013. doi: 10.1021/acs.chemrestox.2c00199. Epub 2022 Oct 27.
2
Developing Structure-Activity Relationships for -Nitrosamine Activity.建立亚硝胺活性的构效关系。
Comput Toxicol. 2021 Nov;20. doi: 10.1016/j.comtox.2021.100186. Epub 2021 Sep 8.
3
Animal Models: A Useful Tool to Unveil Metabolic Changes in Hepatocellular Carcinoma.动物模型：揭示肝细胞癌代谢变化的有用工具。
Cancers (Basel). 2020 Nov 10;12(11):3318. doi: 10.3390/cancers12113318.
4
MicroRNAs in Animal Models of HCC.肝癌动物模型中的微小RNA
Cancers (Basel). 2019 Dec 1;11(12):1906. doi: 10.3390/cancers11121906.
5
The sequential analysis of liver cell necrosis: inhibition of diethylnitrosamine- and dimethylnitrosamine-induced acute liver cell death by posttreatment with diethyldithiocarbamate.肝细胞坏死的序贯分析：用二乙基二硫代氨基甲酸盐进行后处理对二乙基亚硝胺和二甲基亚硝胺诱导的急性肝细胞死亡的抑制作用
Am J Pathol. 1980 Apr;99(1):159-74.
6
Methylation of ribonucleic acid and deoxyribonucleic acid and tumour induction in livers of hypophysectomized rats treated with dimethylnitrosamine.用二甲基亚硝胺处理的垂体切除大鼠肝脏中核糖核酸和脱氧核糖核酸的甲基化与肿瘤诱导
Biochem J. 1968 Feb;106(3):767-8. doi: 10.1042/bj1060767.
7
Biochemical patterns in brain tumours. 3. Transfer ribonucleic acid.脑肿瘤中的生化模式。3. 转移核糖核酸
Acta Neurochir (Wien). 1969;21(2):123-37. doi: 10.1007/BF01540920.
8
The carcinogenic effect of 2-oxo-propyl-propylnitrosamine in Sprague-Dawley rats.2-氧代丙基丙基亚硝胺对斯普拉格-道利大鼠的致癌作用。
Z Krebsforsch Klin Onkol Cancer Res Clin Oncol. 1974 Mar 14;81(1):23-8. doi: 10.1007/BF00303597.
9
[Histochemical investigations of carcinogenesis in rat liver after continuous application of diethylnitrosamine].
Z Krebsforsch. 1969;72(3):226-39.
10
[Enzyme histochemical and radioautographic studies during cancerization of the rat liver with diethylnitrosamine].[用二乙基亚硝胺诱导大鼠肝脏癌变过程中的酶组织化学和放射自显影研究]
Z Krebsforsch. 1968;70(3):252-66.

本文引用的文献

1
The decomposition and toxicity of dialkylnitrosamines in rats.大鼠中二烷基亚硝胺的分解与毒性
Biochem J. 1962 Oct;85(1):72-91. doi: 10.1042/bj0850072.
2
The reaction of mono- and di-functional alkylating agents with nucleic acids.单官能和双官能烷基化剂与核酸的反应。
Biochem J. 1961 Sep;80(3):496-503. doi: 10.1042/bj0800496.
3
The purine and pyrimidine composition of deoxypentose nucleic acids.脱氧戊糖核酸的嘌呤和嘧啶组成。
Biochem J. 1951 May;48(5):584-90. doi: 10.1042/bj0480584.
4
The effect of cysteine on the metabolic changes produced by two carcinogenic Nnitrosodialklamines in rat liver.半胱氨酸对两种致癌性N-亚硝基二烷胺在大鼠肝脏中产生的代谢变化的影响。
Cancer Res. 1962 Apr;22:339-51.
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Toxic liver injury and carcinogenesis. Methylation of proteins of rat-liver slices by dimethylnitrosamine in vitro.中毒性肝损伤与致癌作用。二甲基亚硝胺在体外对大鼠肝切片蛋白质的甲基化作用。
Biochem J. 1962 Apr;83(1):106-14. doi: 10.1042/bj0830106.
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Toxic liver injury and carcinogenesis. Methylation of rat-liver nucleic acids by dimethylnitrosamine in vivo.毒性肝损伤与致癌作用。二甲基亚硝胺在体内对大鼠肝脏核酸的甲基化作用。
Biochem J. 1962 Apr;83(1):114-24. doi: 10.1042/bj0830114.
7
Induction of kidney tumours in the rat with dimethylnitrosamine (N-nitrosodimethylamine).用二甲基亚硝胺（N-亚硝基二甲胺）诱导大鼠肾肿瘤。
J Pathol Bacteriol. 1962 Jul;84:19-31. doi: 10.1002/path.1700840103.
8
Toxic liver injury. Inhibition by dimethylnitrosamine of incorporation of labelled amino acids into proteins of rat-liver preparations in vitro.中毒性肝损伤。二甲基亚硝胺对体外标记氨基酸掺入大鼠肝脏制剂蛋白质的抑制作用。
Biochem J. 1960 Jul;76(1):109-16. doi: 10.1042/bj0760109.
9
REACTION OF THE CARCINOGEN DIMETHYLNITROSAMINE WITH NUCLEIC ACIDS IN VIVO.致癌物二甲基亚硝胺在体内与核酸的反应。
Biochem J. 1963 Oct;89(1):32-7. doi: 10.1042/bj0890032.
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Carcinogenesis and cancer prevention.致癌作用与癌症预防。
Nature. 1963 Mar 23;197:1145-51. doi: 10.1038/1971145a0.

Cellular injury and carcinogenesis. Alkylation of ribonucleic acid of rat liver by diethylnitrosamine and n-butylmethylnitrosamine in vivo.

作者信息

Magee P N, Lee K Y

出版信息

Biochem J. 1964 Apr;91(1):35-42. doi: 10.1042/bj0910035.

DOI:10.1042/bj0910035
PMID:5833387
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1202812/
Abstract
摘要