聚维酮碘和硝噻唑啉中甲醛的释放。

Release of formaldehyde from polynoxylin and noxythiolin.

作者信息

Kingston D

出版信息

J Clin Pathol. 1965 Sep;18(5):666-7. doi: 10.1136/jcp.18.5.666.

DOI:10.1136/jcp.18.5.666

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC473043/

Abstract

Polynoxylin and noxythiolin (Anaflex and Noxyflex) have been recommended for the treatment of certain bacterial infections. Both compounds were shown to release formaldehyde. Detailed studies with noxythiolin showed that it decomposed in solution to liberate most of its formaldehyde, and that solutions of formaldehyde of the appropriate strength gave zones of inhibition on seeded plates comparable in size with those given by noxythiolin. It is suggested that the effects observed with these compounds are caused by the formaldehyde released.

摘要

聚羟甲酚和硝羟喹啉（Anaflex和Noxyflex）已被推荐用于治疗某些细菌感染。这两种化合物都被证明会释放甲醛。对硝羟喹啉的详细研究表明，它在溶液中分解以释放大部分甲醛，并且适当强度的甲醛溶液在接种平板上产生的抑菌圈大小与硝羟喹啉产生的抑菌圈相当。有人认为，观察到的这些化合物的作用是由释放的甲醛引起的。

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本文引用的文献

1

POLYOXYMETHYLENEUREA IN OTOLOGY.聚氧化亚甲基脲在耳科学中的应用

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Self-disinfecting surface coatings which evolve formaldehyde.可释放甲醛的自消毒表面涂层。

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A misapplication of the sensitivity test. Mandelamine discs.敏感性试验的错误应用。乌洛托品药敏纸片。

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The colorimetric estimation of formaldehyde by means of the Hantzsch reaction.通过汉茨希反应对比色法测定甲醛。

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