Williams R J, Hamilton-Miller J M, Brumfitt W
Infection. 1976;4(2):31-4. doi: 10.1007/BF01638345.
A 1.5% glycine solution has recently been introduced as a bladder irrigation fluid. In this study, glycine solution was compared with two other recognised bladder irrigants (chlorhexidine and noxythiolin) for its inhibitory activity against common urinary tract pathogens. Glycine solution supported the growth of nearly 50% of the bacterial strains tested whereas chlorhexidine and noxythiolin were completely inhibitory. In quantitative studies with selected strains it was found that growth could be initiated from as few as 200 organisms/ml. It was concluded that glycine solution was capable of supporting bacterial growth and thus, from a microbiological viewpoint, was unsuitable as a bladder irrigant.
最近，一种1.5%的甘氨酸溶液被用作膀胱冲洗液。在本研究中，将甘氨酸溶液与其他两种公认的膀胱冲洗剂（洗必泰和硝噻唑啉）对常见尿路病原体的抑制活性进行了比较。甘氨酸溶液能支持近50%受试菌株的生长，而洗必泰和硝噻唑啉则具有完全抑制作用。在对选定菌株的定量研究中发现，每毫升低至200个菌体就能开始生长。得出的结论是，甘氨酸溶液能够支持细菌生长，因此，从微生物学角度来看，它不适合作为膀胱冲洗剂。
