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一项关于患桥本甲状腺炎的三胞胎的研究。

A study of triplets with Hashimoto's thyroiditis.

作者信息

McGregor A M, Roberts D F, Hall R

出版信息

Postgrad Med J. 1979 Dec;55(654):894-6. doi: 10.1136/pgmj.55.650.894.

Abstract

Genetic predisposition to Hashimoto's thyroiditis is suggested by its striking aggregation in families and its occurrence in twins. The manifestations range from overt clinical and biochemical hypothyroidism to the detection of thyroid autoantibodies in healthy, symptom-free individuals and their relatives. So far as the authors are aware, the finding of Hashimoto's thyroiditis in identical triplets has not previously been reported and they therefore present the cases of Faith, Hope and Charity, 63-year-old triplet sisters.

摘要

桥本甲状腺炎在家族中的显著聚集现象及其在双胞胎中的发病情况提示了其存在遗传易感性。其表现范围从明显的临床和生化性甲状腺功能减退到在健康、无症状个体及其亲属中检测到甲状腺自身抗体。就作者所知,同卵三胞胎中出现桥本甲状腺炎的情况此前尚未见报道,因此他们报告了63岁的三胞胎姐妹费思、霍普和查丽蒂的病例。

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